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so they really are a one- stop- shop to totally manage your pain and anxiety. many people use kratom to self- treat symptoms of depression or anxiety. best buy overnight shipping. although some evidence suggests that certain strains can successfully help depression and anxiety symptoms, more research is. kratom for anxiety helps improve the sleeping pattern, hence can be useful in dealing with anxiety- induced sleeplessness. sizes of gel capsules. kratom is rich in a class of compounds called alkaloids. the compounds alter physiological and neurological processes in the body, producing relaxation and calmness.